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KMID : 1144320130450040446
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감염과 화학요법
2013 Volume.45 No. 4 p.446 ~ p.450
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First Case of Bartonella henselae Bacteremia in Korea
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Im Jae-Hyoung
Baek Ji-Hyeon
Lee Hyun-Jung
Lee Jin-Soo
Chung Moon-Hyun
Kim Mi-Jeong
Lee Sun-Myoung
Kang Jae-Seung
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Abstract
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Bartonella henselae causes cat-scratch disease, bacteremia, and various focal infections. Despite the worldwide occurrence of B. henselae infections, reports in humans are rare in Korea. The clinical manifestation of all 5 previously reported cases was lymphadenopathy. Herein, we report a case of bacteremia in a woman who presented with prolonged fever. B. henselae was isolated from a blood specimen by cell culture. Conventional polymerase chain reaction amplification and sequencing of the 16S-23S rRNA intergenic space region confirmed the isolate to be B. henselae. The patient had no underlying immunocompromising conditions and no recent exposure to animals. She was successfully managed with a combination of doxycycline and hydroxychloroquine.
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KEYWORD
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Bartonella henselae, Bacteremia, Fever of unknown origin, Doxycycline, Chloroquine
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